EVALUATION OF ANTIHYPERTENSION TREATMENT IN PRE-ECLAMPSIA PATIENTS AT PKU MUHAMMADIYAH PEKAJANGAN ISLAMIC HOSPITAL
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Abstract
Pre-eclampisa is a complication condition of patients at 20 weeks of pregnancy. Based on data from the Pekalongan Regency Health Office, the number of pre-eclampsia patients increases every year. Pre-eclampsia patients need to be given antihypertensive therapy in lowering blood pressure and reducing the high risk of pre-eclampsia. Evaluating the suitability of antihypertensive treatment in pre-eclampsia at RSI PKU Muhammadiyah Pekajangan with the right drug, right indications, right dose, and right patient is the purpose of this study. The research was conducted in a non-experimental manner that was descriptive analysis. Data was collected by retrospective method from medical records at the inpatient installation of RSI PKU Muhammadiyah Pekajangan for the July-December 2022 period of 31 patients. The patient criteria are inclusion criteria where severe pre-eclampsia patients without comorbidities and receive antihypertensive treatment. The research data were analyzed quantitatively. The results showed the suitability of the drug based on the right patient by 96.77%, the right indication by 96.77%, the right drug by 96.77%, and the right dose by 100%. Severe pre-eclampsia patients used more antihypertensive monotherapy and drug suitability results was 97.57%. The government needs to collaborate among stakeholders such as the Health Service, Hospitals, Community Health Centers, Midwives, Districts, and Sub-Districts by approaching the community for screening of pregnant women. The collaboration is expected to encourage more comprehensive health data collection of pregnant women, encourage public awareness about the health of pregnant women, measure the effectiveness of pre-eclampsia treatment, develop consistent and quality pre-eclampsia handling protocols, as well as monitoring, mentoring and evaluating the health condition of pregnant women.
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References
Administration, F. D. and. (2023a). Captopril/hydrochlorothiazide Pregnancy and Breastfeeding Warnings. Retrieved July 21, 2023, from https://www.drugs.com/pregnancy/captopril-hydrochlorothiazide.html
Administration, F. D. and. (2023b). Nifedipine Pregnancy and Breastfeeding Warnings. Retrieved July 21, 2023, from https://www.drugs.com/pregnancy/nifedipine.html
Andriana Dwi, D., Utami Dyah, E., & Sholihat Kurnia, N. (2018). Evaluasi Penggunaan Obat Antihipertensi pada Pasien Pre-eklampsia Rawat Inap di RSUD Prof, Dr. Margono Soekarjo Purwokerto. Acta Pharmaciae Indonesia : Acta Pharm Indo, 6(1), 29. https://doi.org/10.5281/zenodo.3707186
Dewi, K., & Rarashita, N. M. (2021). Pola Pengobatan Antihipertensi pada Pasien Preeklampsia di Rumah Sakit Harapan Bunda. Jurnal Sosial Sains, 1(7), 637–644. https://doi.org/10.36418/sosains.v1i7.143
Farahdini, Y. (2020). Hubungan Asupan Lemak, Asupan Garam dan Status Gizi dengan Tekanan Darah Penderita Hipertensi di UPT. Puskesmas Singkawang Timur I. Jurnal Borneo Akcaya, 6(2), 111–120.
Guidelines, Q. C. (2021). Maternity and Neonatal Clinical Guideline. Queensland Health, 1–39.
Izza, N., Kusdiyah, E., & Maharani, C. (2022). Gambaran Karakteristik dan Faktor Risiko Preeklampsia di Puskesmas Kota Jambi Tahun 2017-2021. Journal Of Medical Studies, 2(2), 38–60.
Kundarto, W., & Faizah, R. N. (2021). Evaluasi Terapi Antihipertensi Pada Pasien Preeklampsia Berat di Instalasi Rawat Inap RSUD Dr. Moewardi Periode Januari - Juni Tahun 2017. JPSCR: Journal of Pharmaceutical Science and Clinical Research, 6(2), 228. https://doi.org/10.20961/jpscr.v6i2.39487
NICE. (2022). Hypertension in pregnancy : diagnosis and management. National Institute for Health and Care Excellence, 77(1), S1-s22. Retrieved from https://www.nice.org.uk/guidance/ng133/resources/hypertension-in-pregnancy-diagnosis-and-management-pdf-66141717671365
Nurmainah, N., Hadad, F. M., & Andrie, M. (2021). Profil Proteinuria dan Tekanan Darah pada Pasien Preeklampsia Berat yang menggunakan Antihipertensi. Indonesian Journal of Clinical Pharmacy, 10(2), 79. https://doi.org/10.15416/ijcp.2021.10.2.79
Peraturan Daerah Kabupaten Pekalongan Nomor 1 Tahun 2022 Tentang Pencegahan dan Penanggulangan penyakit. (2022). Retrieved July 21, 2023, from https://peraturan.bpk.go.id/Details/221127/perda-kab-pekalongan-no-1-tahun-2022
POGI. (2016). PNPK Diagnosis dan Tatalaksana Preeklampsia. 1–48.
Population, G., Ages, A., & Ages, A. (2014). JNC 8 Hypertension Guideline Algorithm. 311(5).
Qoyimah, U. N. (2016). Evaluation of the Use of Antihypertensive Drugs on Inpatient with Preeclampsia at PKU Muhammadiyah Hospital Bantul Period January-December 2015. Jurnal Ilmiah Ibnu Sina, 1(2), 192–202.
Rachmaini, F., Juwita, D. A., Abdillah, R., & Rifqi, M. A. (2023). Pengaruh Penggunaan Obat Antihipertensi Terhadap Tekanan Darah Dan Proteinuria Pada Pasien Preeklampsia Berat Di RSUP Dr. M. Djamil. Jurnal Sains Farmasi & Klinis, 9(sup), 175. https://doi.org/10.25077/jsfk.9.sup.175-183.2022
Ramadhan, M. F. Y., Mulyani, T., Ariyani, H., Farmasi, F., Muhammadiyah, U., & Obat, P. (2022). Evaluasi Penggunaan Obat Antihipertensi Pada Pasien Di RSUD Datu Sanggul Rantau. Journal Current Pharmaceutical Sciences, 5(2), 514–523.
Rohmani, A., Setyabudi, M. T., & Puspitasari, D. R. (2015). Faktor Resiko Kejadian Hipertensi dalam Kehamilan. Fakultas Kedokteran Universitas Muhammadiyah Semarang, 4, 1–9.
Setyawan, J. F. D., Wiryanthini, I. A. D., & Tianing, N. W. (2019). Gambaran Kadar Protein Urine pada Ibu Hamil Preeklampsia dan Eklampsia di RSUP Sanglah Denpasar Tahun 2017. Jurnal Medika Udayana, 8(12), 1–5. Retrieved from https://ojs.unud.ac.id
Sukma, A. (2021). Evaluasi Efektivitas Penggunaan Obat Antihipertensi Pada Pasien Pre-eklampsia Rawat Inap Di RSUD Caruban.
Tahar, N., Sakti Parenta, E. D., Febriyanti, A. P., Rusdi, M., & Al Kautsar, A. M. (2021). Evaluasi Tepat Penggunaan Obat Lini Pertama dan Lini Kedua Antihipertensi pada Pasien Preeklampsia: A Literatur Review. Jurnal Midwifery, 3(2), 52–68. https://doi.org/10.24252/jmw.v3i2.24341
Ulfah, A. A. (2020). Gambaran Karakteristik Kejadian Preeklampsia Pada Ibu Hamil : Studi Literatur Review.
Velga, Y., & Suryani, U. (2022). Faktor Yang Berhubungan Dengan Tingkat Stres Pada Ibu Hamil Dalam Menghadapi Persalinan. JKJ): Persatuan Perawat Nasional Indonesia, 10(4), 837–856.
Wafiyatunisa, Z., & Rodiani. (2016). Hubungan Obesitas dengan Terjadinya Preeklampsia Obesity Relationship with the Occurrence of Preeclampsia. Majority, 5(5), 184–190. Retrieved from http://juke.kedokteran.unila.ac.id/index.php/majority/article/view/907/815
Yani, Y. A., Oktavia, N., & Rame, M. M. T. (2021). Evaluasi Penggunaan Obat Antihipertensi Pasien Preeklampsia di Instalasi Rawat Inap RSUD Prof. Dr. W.Z Johannes Kupang. CHM-K Pharmaceutical Scientific Journal, 4(1), 242–248.
Yulianti, W., Permadi, Y. W., Zuhana, N., & Muthoharoh, A. (2018). Efektivitas Penggunaan Obat Antihipertensi pada Preeklampsia di Instalasi Rawat Inap RSUD Kajen Kabupaten Pekalongan Periode Januari-Desember Tahun 2018. Universitas Muhammadiyah Pekajangan Pekalongan, 1–11. Retrieved from https://docplayer.info/185371420-Efektivitas-penggunaan-obat-antihipertensi-pada-preeklampsia-di-instalasi-rawat-inap-rsud-kajen-kabupaten-pekalongan-periode-januari-desember-tahun.html